Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29229446 | 1.00 | ALDH1A1 (0.69) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL22720116 | 0.98 | ALDH1A1 (0.66) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL13161898 | 0.95 | ALDH1A1 (0.61) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL2060435 | 0.91 | CRBN (0.56) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| Water SCHEMBL28110279 | 0.90 | CRBN (0.55) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL30666379 | 0.86 | ALDH1A1 (0.77) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL27647724 | 0.85 | ALDH1A1 (0.58) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL2771766 | 0.85 | CRBN (0.51) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL28510668 | 0.85 | CRBN (0.51) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL2771765 | 0.85 | CRBN (0.51) | ALDH1A1KDM4ENPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184588-A | N-aryl/alkyl quinazolinone compound and synthesis method thereof | 陕西科技大学 | 2024-06-14 | — | — | CN | claimed |
| CN-118184588-A | N-aryl/alkyl quinazolinone compound and synthesis method thereof | 陕西科技大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-114276203-B | Method for synthesizing 2-aminobenzamide compound by ultraviolet light induction | 湖南大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-114276203-A | Method for synthesizing 2-aminobenzamide compound by ultraviolet light induction | 湖南大学 | 2022-04-05 | — | — | CN | disclosed |
| WO-2020239050-A1 | 2-(2-CHLORO-4-METHYLPHENYL)QUINAZOLINE-4(3H)-KETONE COMPOUND AND MEDICAL USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2020-12-03 | — | — | WO | disclosed |
| CN-110041272-B | 2- (2-chlorphenyl) quinazoline-4 (3H) -ketone derivative and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-30 | — | — | CN | disclosed |
| CN-110041273-B | 2- (2-chloro-4-methylphenyl) quinazoline-4 (3H) -ketone compound and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-20 | — | — | CN | disclosed |
| CN-110041272-A | 2- (2- chlorphenyl) quinazoline -4 (3H) -one analog derivative and its preparation method and application | 中国人民解放军军事科学院军事医学研究院 | 2019-07-23 | — | — | CN | disclosed |
| EP-3056207-B1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMA CO LTD (JP) | 2018-06-20 | — | — | EP | disclosed |
| EP-3056207-B1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMA CO LTD (JP) | 2018-06-20 | — | — | EP | disclosed |
| US-5571832-A | Nitrogen-containing cyclohetero alkylamino aryl derivatives for CNS disorders | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-11-05 | — | — | US | disclosed |
| US-5346908-A | Anticonvulsant | NATIONAL INSTITUTES OF HEALTH (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0594597-A1 | NITROGEN-CONTAINING CYCLOHETERO CYCLOALKYLAMINOARYL DERIVATIVES FOR CNS DISORDERS | G.D. Searle & Co. (US) | 1994-05-04 | — | — | EP | disclosed |
| WO-1994006794-A1 | ARALKYL DIAZABICYCLOALKANE DERIVATIVES FOR CNS DISORDERS | NATIONAL INSTITUTES OF HEALTH (US) | 1994-03-31 | — | — | WO | disclosed |
| EP-0594597-A4 | NITROGEN-CONTAINING CYCLOHETERO CYCLOALKYLAMINOARYL DERIVATIVES FOR CNS DISORDERS. | SEARLE & CO (US) | 1993-04-30 | — | — | EP | disclosed |
| WO-1992022279-A2 | N-[ARYLETHYL]-N-ALKYL-2-(1-PYRROLIDINYL)ETHYLAMINE DERIVATIVES FOR CNS DISORDERS | G.D. SEARLE & CO. (US) | 1992-12-23 | — | — | WO | disclosed |
| EP-0518216-A2 | N-/Arylethyl/-N-alkyl-2-(1-pyrrolidinyl)ethylamine derivatives for CNS disorders | G.D. Searle & Co. (US) | 1992-12-16 | — | — | EP | disclosed |
| US-5130330-A | Central nervous system disorders, antiischemic agents, psychotic disorders and anticonvulsants | G. D. SEARLE & CO. (US) | 1992-07-14 | — | — | US | disclosed |
| WO-1992004017-A1 | CIS-N-(2-AMINOCYCLOHEXYL)BENZAMIDE AND THEIR ENANTIOMERS AS ANTICONVULSANTS | THE UPJOHN COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |
| WO-1991012247-A1 | NITROGEN-CONTAINING CYCLOHETERO CYCLOALKYLAMINOARYL DERIVATIVES FOR CNS DISORDERS | G.D. SEARLE & CO. (US) | 1991-08-22 | — | — | WO | disclosed |