Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.47 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2771766 | 1.00 | CRBN (0.51) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2771765 | 1.00 | CRBN (0.51) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2060435 | 0.93 | CRBN (0.56) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| Water SCHEMBL28110279 | 0.92 | CRBN (0.55) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL4960760 | 0.87 | NPC1 (0.53) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL22720116 | 0.87 | ALDH1A1 (0.66) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL13161898 | 0.87 | ALDH1A1 (0.61) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL13634186 | 0.86 | RAB9A (0.59) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL22720137 | 0.86 | RAB9A (0.59) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2154833 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4ENPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341347-B | Synthetic method of ambroxol hydrochloride | 中国药科大学 | 2022-03-08 | — | — | CN | claimed |
| CN-112341347-A | Synthetic method of ambroxol hydrochloride | 中国药科大学 | 2021-02-09 | — | — | CN | claimed |
| CN-117886699-A | New process for synthesizing ambroxol hydrochloride intermediate | 江苏阿尔法药业股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-112341347-B | Synthetic method of ambroxol hydrochloride | 中国药科大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-112341347-B | Synthetic method of ambroxol hydrochloride | 中国药科大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-112341347-A | Synthetic method of ambroxol hydrochloride | 中国药科大学 | 2021-02-09 | — | — | CN | disclosed |
| CN-112341347-A | Synthetic method of ambroxol hydrochloride | 中国药科大学 | 2021-02-09 | — | — | CN | disclosed |