Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.74 |
| ▸ | CA4 | P22748 | 3/20 | 0.74 |
| ▸ | CA6 | P23280 | 3/20 | 0.74 |
| ▸ | CA5A | P35218 | 3/20 | 0.74 |
| ▸ | CA7 | P43166 | 3/20 | 0.74 |
| ▸ | CA9 | Q16790 | 3/20 | 0.74 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.74 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.68 |
| ▸ | APP | P05067 | 10/20 | 0.66 |
| ▸ | MAPT | P10636 | 10/20 | 0.66 |
| ▸ | BACE1 | P56817 | 5/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.66 |
| ▸ | MAOA | P21397 | 2/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509085 | 0.89 | ALOX5 (0.84) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL9695487 | 0.89 | ALOX5 (0.84) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL9534270 | 0.89 | APP (0.74) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL9534272 | 0.89 | APP (0.74) | CA12CA4CA6CA5ACA7 | |
| Curcumin SCHEMBL23071393 | 0.86 | APP (0.84) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL3198103 | 0.86 | APP (0.84) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL3198089 | 0.86 | APP (0.84) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL25512244 | 0.82 | APP (0.65) | CA12CA4CA6CA5ACA7 | |
| Curcumin SCHEMBL9777882 | 0.82 | APP (0.76) | CA12CA4CA6CA5ACA7 | |
| Curcumin SCHEMBL9777883 | 0.82 | APP (0.76) | CA12CA4CA6CA5ACA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564204-A1 | 1,5-DIPHENYL-PENTA-1,4-DIEN-3-ONE COMPOUNDS | The University of Tokyo (JP) | 2019-11-06 | — | — | EP | disclosed |