Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.84 |
| ▸ | APP | P05067 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | TTR | P02766 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 3/20 | 0.71 |
| ▸ | CA4 | P22748 | 3/20 | 0.71 |
| ▸ | CA6 | P23280 | 3/20 | 0.71 |
| ▸ | CA5A | P35218 | 3/20 | 0.71 |
| ▸ | CA7 | P43166 | 3/20 | 0.71 |
| ▸ | CA9 | Q16790 | 3/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.71 |
| ▸ | KDM1A | O60341 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | BACE1 | P56817 | 3/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509085 | 1.00 | ALOX5 (0.84) | ALOX5APPMAPTTTRCYP2D6 | |
| SCHEMBL3686080 | 0.91 | ALOX5 (1.00) | ALOX5APPMAPTTTRCYP2D6 | |
| SCHEMBL9533683 | 0.91 | ALOX5 (1.00) | ALOX5APPMAPTTTRCYP2D6 | |
| SCHEMBL30219096 | 0.91 | ALOX5 (1.00) | ALOX5APPMAPTTTRCYP2D6 | |
| SCHEMBL9534272 | 0.90 | APP (0.74) | ALOX5APPMAPTCYP2D6CA12 | |
| SCHEMBL9534270 | 0.90 | APP (0.74) | ALOX5APPMAPTCYP2D6CA12 | |
| SCHEMBL21548781 | 0.89 | CA12 (0.74) | ALOX5APPMAPTTTRCYP2D6 | |
| SCHEMBL10467071 | 0.88 | ALOX5 (1.00) | ALOX5APPMAPTTTRCYP2D6 | |
| SCHEMBL10467072 | 0.88 | ALOX5 (1.00) | ALOX5APPMAPTTTRCYP2D6 | |
| SCHEMBL9695786 | 0.88 | APP (0.76) | ALOX5APPMAPTTTRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142095-A | Treating inflammation, allergies, asthma, cardiovascular disorders, psoriasis | WARNER-LAMBERT COMPANY (US) | 1992-08-25 | — | — | US | claimed |