Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21526064 | 0.93 | GPR6 (0.39) | TLR7MEN1KMT2ANPSR1 | |
| SCHEMBL21526104 | 0.77 | SMN1; SMN2 (0.38) | TLR7MAPTMAPK1CASP3BLM | |
| SCHEMBL20356749 | 0.76 | SMN1; SMN2 (0.43) | TLR7NPSR1 | |
| Hydrochloric Acid SCHEMBL21526020 | 0.75 | SMN1; SMN2 (0.42) | TLR7NPSR1 | |
| SCHEMBL21526073 | 0.74 | SMN1; SMN2 (0.44) | KDM4EALDH1A1NPSR1 | |
| SCHEMBL21548809 | 0.73 | SMN1; SMN2 (0.43) | MAPTKDM4EALDH1A1NPSR1TDP1 | |
| Hydrochloric Acid SCHEMBL21526024 | 0.73 | SMN1; SMN2 (0.43) | MAPTKDM4EALDH1A1NPSR1TDP1 | |
| Hydrochloric Acid SCHEMBL21526127 | 0.73 | SMN1; SMN2 (0.43) | KDM4EALDH1A1NPSR1 | |
| SCHEMBL21548806 | 0.71 | SMN1; SMN2 (0.44) | KMT2AALDH1A1NPSR1 | |
| SCHEMBL21548948 | 0.71 | PKM (0.36) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564216-B1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| EP-3564216-A1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-11-06 | — | — | EP | disclosed |