Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PER2 | O15055 | 1/20 | 0.34 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.34 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21549481 | 0.91 | RORC (0.39) | RORCSMN1; SMN2NPY5RKDM4ETP53 | |
| SCHEMBL20183809 | 0.90 | MAPT (0.40) | RORCSMN1; SMN2NPY5RKDM4ETP53 | |
| SCHEMBL20183843 | 0.89 | RORC (0.44) | RORCSMN1; SMN2NPY5RKDM4ETP53 | |
| SCHEMBL20183702 | 0.88 | RORC (0.52) | RORC | |
| SCHEMBL20183608 | 0.85 | RORC (0.38) | RORCSMN1; SMN2NPY5RKDM4ETP53 | |
| SCHEMBL20354318 | 0.84 | KDM4E (0.42) | RORCSMN1; SMN2KDM4ETP53MAPT | |
| SCHEMBL20183791 | 0.84 | ALDH1A1 (0.38) | RORCSMN1; SMN2NPY5RKDM4ETP53 | |
| SCHEMBL20183650 | 0.83 | ALDH1A1 (0.41) | RORCSMN1; SMN2KDM4ETP53MAPT | |
| SCHEMBL20183556 | 0.83 | RORC (0.38) | RORCSMN1; SMN2NPY5RKDM4ETP53 | |
| SCHEMBL20183854 | 0.83 | ALDH1A1 (0.42) | RORCSMN1; SMN2NPY5RKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3563851-A1 | ANTITUMOR AGENT AND BROMODOMAIN INHIBITOR | FUJIFILM Corporation (JP) | 2019-11-06 | — | — | EP | disclosed |