Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.56 |
| ▸ | CDK2 | P24941 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 4/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335722 | 0.90 | FGFR1 (0.51) | CDK1CCNB1CCNE1CDK2CYP3A4 | |
| SCHEMBL28083709 | 0.80 | CDK1 (0.63) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL5161136 | 0.74 | ADORA2A (0.59) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL21533660 | 0.74 | CDK1 (0.56) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL8767031 | 0.73 | CCNE1 (1.00) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL5161691 | 0.72 | ADORA2A (0.63) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL5164664 | 0.72 | ADORA2A (0.61) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL15354451 | 0.71 | CDK1 (0.73) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL5161756 | 0.71 | CDK1 (0.73) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL3931613 | 0.71 | TLR7 (0.49) | CYP3A4PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343056-A1 | Producing stable adefovir dipivoxil solid dispersions | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi (TR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2011080704-A1 | PRODUCING STABLE ADEFOVIR DIPIVOXIL SOLID DISPERSIONS IN AMORPHOUS STATE | ABDI IBRAHIM ILAC SANAYI VE TICARET ANONIM SIRKETI (TR) | 2011-07-07 | — | — | WO | disclosed |