Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.51 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154971 | 0.90 | CDK1 (0.56) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL28476413 | 0.80 | ADORA2A (0.57) | ADORA2AADORA1ADORA2BTMIGD3CYP3A4 | |
| SCHEMBL1377647 | 0.74 | CDK1 (0.76) | ADORA2AADORA1ADORA2BTMIGD3CYP3A4 | |
| Pmedap SCHEMBL215611 | 0.74 | FGFR1 (0.72) | FGFR1SLC22A6CYP3A4CDK1CCNB1 | |
| Pmedap SCHEMBL29571667 | 0.74 | FGFR1 (0.72) | FGFR1SLC22A6CYP3A4CDK1CCNB1 | |
| SCHEMBL5162224 | 0.74 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BTMIGD3 | |
| SCHEMBL19553577 | 0.73 | ADORA2A (0.51) | ADORA2AADORA1ADORA2BTMIGD3CDK1 | |
| SCHEMBL5161193 | 0.73 | ADORA2A (0.67) | ADORA2AADORA1ADORA2BTMIGD3 | |
| SCHEMBL232387 | 0.73 | ADORA2A (0.62) | ADORA2AADORA1ADORA2BTMIGD3CYP3A4 | |
| SCHEMBL28420439 | 0.73 | FGFR1 (0.59) | FGFR1SLC22A6CYP3A4HPRT1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935946-A | TENOFOVIR DISOPROXIL FUMARATE; ANTIVIRAL THERAPY | GILEAD SCIENCES, INC. (US) | 1999-08-10 | — | — | US | disclosed |