Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | OAT | P04181 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36839 | 0.68 | — | — | |
| Bromide SCHEMBL28859971 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL9359992 | 0.66 | — | — | |
| SCHEMBL3706343 | 0.63 | — | — | |
| SCHEMBL7167115 | 0.63 | — | — | |
| SCHEMBL484082 | 0.60 | CES2 (0.40) | GABRR1TSHROATTDP1 | |
| SCHEMBL2410832 | 0.60 | GABRR1 (0.34) | GABRR1TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL366225 | 0.59 | GABRR1 (0.33) | GABRR1TSHRMAPK1HSD17B10OAT | |
| SCHEMBL23706926 | 0.57 | ABAT (0.47) | GABRR1TSHRMAPK1HSD17B10OAT | |
| Hydrochloric Acid SCHEMBL23699861 | 0.56 | ABAT (0.46) | GABRR1TSHRMAPK1HSD17B10OAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019214587-A1 | DEUTERATED DEFACTINIB COMPOUND AND USE THEREOF | 成都海创药业有限公司 (CN) | 2019-11-14 | — | — | WO | disclosed |