SCHEMBL484082

SCHEMBL484082

CC1CCC(C(=O)O)=CO1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.40
TSHR P16473 2/20 0.40
LMNA P02545 1/20 0.40
OAT P04181 1/20 0.36
CA1 P00915 1/20 0.34
CA9 Q16790 1/20 0.34
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
GABRR1 P24046 2/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31
GABRA4 P48169 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7167115 0.79
SCHEMBL2143646 0.77 CES2 (0.35) CES2TSHRLMNAOATCA1
SCHEMBL2410830 0.76 CES2 (0.37) CES2TSHRLMNAOATMAPT
SCHEMBL1908179 0.75 OAT (0.34) OAT
SCHEMBL4112454 0.72 CES2 (0.37) CES2TSHRLMNAOATMAPT
Propionic Acid SCHEMBL11638646 0.71 FFAR3 (0.34) CA1CA9MAPT
SCHEMBL20057247 0.70 NLRP3 (0.36) CES2TSHRLMNAMAPT
SCHEMBL545207 0.68
SCHEMBL2410832 0.68 GABRR1 (0.34) CES2TSHRMAPTTDP1GABRR1
SCHEMBL11639988 0.67 ALDH1A1 (0.35) TSHRMAPTGABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338529-B2 Oil repellent copolymer, method for its production and oil repellent treatment solution ASAHI GLASS COMPANY, LIMITED (JP) 2012-12-25 US claimed
EP-2103635-B1 OIL-REPELLENT COPOLYMER, METHOD FOR PRODUCING THE SAME AND OIL-REPELLENT PROCESSING LIQUID ASAHI GLASS CO LTD (JP) 2012-09-12 EP claimed
EP-4353758-A1 RESIN COMPOSITION, COATING MATERIAL, AND COATED ARTICLE DIC Corporation (JP) 2024-04-17 EP disclosed
US-20240101845-A1 COATED BODY DAI NIPPON TORYO CO., LTD. (JP) 2024-03-28 US disclosed
WO-2022259739-A1 RESIN COMPOSITION, COATING MATERIAL, AND COATED ARTICLE DIC株式会社 2022-12-15 WO disclosed
US-20210340299-A1 POLYCARBONATE-MODIFIED ACRYLIC RESIN, PAINT, AND PLASTIC MOLDED ARTICLE PAINTED BY SAID PAINT DIC CORPORATION (JP) 2021-11-04 US disclosed
US-10941311-B2 Polyoxyethylene compound having multiple hydroxyl groups at end, and contact lens NOF CORPORATION (JP) 2021-03-09 US disclosed
US-20210040339-A1 ACTINIC RADIATION-CURABLE INKJET INK COMPOSITION AND PRINTING METHOD DAI NIPPON TORYO CO., LTD. (JP) 2021-02-11 US disclosed
EP-3766941-A1 ACTINIC-RAY-CURABLE INK-JET INK COMPOSITION AND PRINTING METHOD Dai Nippon Toryo Co., Ltd. (JP) 2021-01-20 EP disclosed
US-10745518-B2 Branching-type polyoxyethylene compound and contact lens NOF CORPORATION (JP) 2020-08-18 US disclosed
US-20190136085-A1 POLYOXYETHYLENE COMPOUND HAVING MULTIPLE HYDROXYL GROUPS AT END, AND CONTACT LENS NOF CORPORATION (JP) 2019-05-09 US disclosed
US-20090281239-A1 OIL REPELLENT COPOLYMER, METHOD FOR ITS PRODUCTION AND OIL REPELLENT TREATMENT SOLUTION ASAHI GLASS COMPANY LIMITED (JP) 2009-11-12 US disclosed
EP-2103635-A1 OIL-REPELLENT COPOLYMER, METHOD FOR PRODUCING THE SAME AND OIL-REPELLENT PROCESSING LIQUID Asahi Glass Company, Limited (JP) 2009-09-23 EP disclosed
US-20090232859-A1 COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-09-17 US disclosed
EP-2100591-A2 Cosmetic comprising a silicone polymer with a benzotriazol residue Shin-Etsu Chemical Co., Ltd. (JP) 2009-09-16 EP disclosed
EP-1618926-B1 HAIR TREATMENT COMPRISING ACRYLIC/SILICONE COPOLYMER AND COSMETIC HAIR PREPARATION CONTAINING THE TREATMENT SHINETSU CHEMICAL CO (JP) 2009-06-03 EP disclosed
US-20060198804-A1 Hair treatment comprising acrylic/silicone copolymer and cosmetic hair preparation containing the treatment SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-09-07 US disclosed
EP-1618926-A1 HAIR TREATMENT COMPRISING ACRYLIC/SILICONE COPOLYMER AND COSMETIC HAIR PREPARATION CONTAINING THE TREATMENT Shin-Etsu Chemical Company, Ltd. (JP) 2006-01-25 EP disclosed
US-20040156809-A1 Acrylic/silicone copolymer having at least one hydrolyzable silyl group; waterproof, sebum resistance, storage stability SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-08-12 US disclosed
EP-1405624-A1 SURFACE-TREATED POWDER AND COSMETIC PREPARATION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-04-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060198804-A1 Hair treatment comprising acrylic/silicone copolymer and cosmetic hair preparation containing the treatment SUCLG1, SGMS1, HDAC10 CES2 379/4885TSHR 3219/4885LMNA 738/4885
US-20090232859-A1 COSMETIC HAX1, HAO1, HAO2 CES2 42/4885TSHR 2030/4885LMNA 3234/4885
US-20040156809-A1 Acrylic/silicone copolymer having at least one hydrolyzable silyl group; waterproof, sebum resistance, storage stability ESPL1, STS, SUCLG1 CES2 790/4885TSHR 4186/4885LMNA 2691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.