SCHEMBL2155002

SCHEMBL2155002

CC(C)COC(=O)C(=Cc1ccc(N)cc1)C(=O)OCC(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
MAPT P10636 4/20 0.49
LMNA P02545 3/20 0.49
NPSR1 Q6W5P4 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
S1PR4 O95977 1/20 0.49
S1PR1 P21453 1/20 0.49
MAPK1 P28482 1/20 0.49
ALDH1A1 P00352 4/20 0.44
TSHR P16473 2/20 0.44
NR1H4 Q96RI1 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MITF O75030 1/20 0.39
HSP90AA1 P07900 1/20 0.39
HTT P42858 1/20 0.39
SCN1A P35498 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14273869 0.86 ALDH1A1 (0.51) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL2215501 0.85 MEN1 (0.67) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL6924253 0.82 MEN1 (0.72) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL10887368 0.82 KMT2A (0.47) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL4137735 0.81 ALDH1A1 (0.53) MEN1KMT2AMAPTMAPK1ALDH1A1
SCHEMBL4137737 0.81 ALDH1A1 (0.53) MEN1KMT2AMAPTMAPK1ALDH1A1
SCHEMBL4000082 0.80 MEN1 (0.41) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL8472995 0.79 KMT2A (0.54) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL4007797 0.79 MEN1 (0.41) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL9453982 0.78 ALDH1A1 (0.53) MEN1KMT2AMAPTLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011080043-A1 UREIDOPYRIMIDONES; COSMETIC USE AS UV-SCREENING AGENTS; ANTISUN COMPOSITIONS CONTAINING THEM L'OREAL (FR) 2011-07-07 WO disclosed
WO-2011080043-A1 UREIDOPYRIMIDONES; COSMETIC USE AS UV-SCREENING AGENTS; ANTISUN COMPOSITIONS CONTAINING THEM L'OREAL (FR) 2011-07-07 WO disclosed
EP-2193784-A1 Cosmetic compositions containing an ester derivative of 2-pyrrolidinone 4-carboxy and a lipophilic triazine filter, with use of said derivative as a solvent of a lipophilic triazine filter L'OREAL (FR) 2010-06-09 EP disclosed
WO-2009074409-A1 S-TRIAZINE COMPOUNDS CONTAINING ONE AMINOSILOXANE GROUP AND TWO PARTICULAR PARA-AMINOBENZALMALONATE GROUPS; COSMETIC COMPOSITIONS CONTAINING SAID DERIVATIVES; USES OF SAID S-TRIAZINE DERIVATIVES L'OREAL (FR) 2009-06-18 WO disclosed
US-6517742-B1 2-(butyl 4'-ylaminobenzoate)-4,6-bis((1,3,3,3-tetramethyl-1 -((trimethylsilyl)oxy)disiloxanyl)propyl-3-ylamino)-s-triazine; s-triazine derivatives substituted by at least one silicone group; from cyanuric chloride L'OREAL (FR) 2003-02-11 US disclosed
US-5252323-A Hair and skin protection from UV RAD L'OREAL (FR) 1993-10-12 US disclosed
US-5236698-A S-TRIAZINE DERIVATIVES CARRYING BENZALMALONATE SUBSTITUENTS, AND COSMETIC UV SCREENING COMPOSITIONS L'OREAL (FR) 1993-08-17 US disclosed