SCHEMBL2215501

SCHEMBL2215501

CC(C)COC(=O)C(=Cc1ccccc1)C(=O)OCC(C)C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.67
KMT2A Q03164 7/20 0.67
ALDH1A1 P00352 5/20 0.56
TSHR P16473 2/20 0.56
NR1H4 Q96RI1 1/20 0.50
MAPT P10636 5/20 0.49
LMNA P02545 3/20 0.49
NPSR1 Q6W5P4 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
S1PR4 O95977 1/20 0.49
S1PR1 P21453 1/20 0.49
MAPK1 P28482 1/20 0.49
KDM4E B2RXH2 2/20 0.44
HPGD P15428 2/20 0.44
HSP90AA1 P07900 1/20 0.44
HTT P42858 1/20 0.44
AKR1C3 P42330 1/20 0.43
PLIN1 O60240 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12663453 0.90 KMT2A (0.55) MEN1KMT2AALDH1A1TSHRNR1H4
SCHEMBL12663633 0.90 KMT2A (0.55) MEN1KMT2AALDH1A1TSHRNR1H4
SCHEMBL14273869 0.87 ALDH1A1 (0.51) MEN1KMT2AALDH1A1TSHRNR1H4
SCHEMBL27765730 0.87 AKR1C3 (0.53) MEN1KMT2AALDH1A1TSHRMAPT
SCHEMBL2155002 0.85 MEN1 (0.49) MEN1KMT2AALDH1A1TSHRNR1H4
SCHEMBL13241269 0.85 KMT2A (0.66) MEN1KMT2AALDH1A1TSHRNR1H4
SCHEMBL10887368 0.83 KMT2A (0.47) MEN1KMT2AALDH1A1TSHRMAPT
SCHEMBL7542791 0.82 ALDH1A1 (0.61) MEN1KMT2AALDH1A1MAPTLMNA
SCHEMBL21457644 0.82 ALDH1A1 (0.61) MEN1KMT2AALDH1A1MAPTLMNA
SCHEMBL7542795 0.82 ALDH1A1 (0.61) MEN1KMT2AALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4457911-A Dialkyl malonates as organic sunscreen adjuvants VAN DYK & COMPANY INC. (US) 1984-07-03 US claimed
EP-0100651-A1 Dialkyl malonates as organic suncreen adjuvants VAN DYK & COMPANY, INC. (US) 1984-02-15 EP claimed
EP-3645625-B1 HIGH STIFFNESS POLYPROPYLENE IMPACT COPOLYMER EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-03-27 EP disclosed
US-11732067-B2 High stiffness polypropylene impact copolymer EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-22 US disclosed
EP-2876118-B1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO LTD (JP) 2022-04-06 EP disclosed
CN-110799549-B Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for propylene polymerization 东邦钛株式会社 2022-03-15 CN disclosed
US-11192965-B2 Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2021-12-07 US disclosed
CN-109694420-B Catalyst system for olefin polymerization, prepolymerized catalyst and olefin polymerization process 中国石油化工股份有限公司 2021-08-03 CN disclosed
US-20210040247-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO., LTD. (JP) 2021-02-11 US disclosed
CN-108473612-B Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer 东邦钛株式会社 2021-02-05 CN disclosed
EP-3404046-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST FOR POLYMERIZATION OF OLEFINS, AND METHOD FOR PRODUCING OLEFIN POLYMERS TOHO TITANIUM CO LTD (JP) 2020-08-19 EP disclosed
EP-2730590-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER Toho Titanium CO., LTD. (JP) 2014-05-14 EP disclosed
CN-103649131-A Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer TOHO TITANIUM CO LTD 2014-03-19 CN disclosed
EP-1952843-B1 Photostable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom MERCK PATENT GMBH (DE) 2011-07-27 EP disclosed
US-20100183530-A1 Cosmetic compositions comprising 4-carboxy-2-pyrrolidinone esters and triazine lipophilic UV-screening agents L'OREAL (FR) 2010-07-22 US disclosed
US-20100183530-A1 Cosmetic compositions comprising 4-carboxy-2-pyrrolidinone esters and triazine lipophilic UV-screening agents L'OREAL (FR) 2010-07-22 US disclosed
EP-2193784-A1 Cosmetic compositions containing an ester derivative of 2-pyrrolidinone 4-carboxy and a lipophilic triazine filter, with use of said derivative as a solvent of a lipophilic triazine filter L'OREAL (FR) 2010-06-09 EP disclosed
WO-2009074409-A1 S-TRIAZINE COMPOUNDS CONTAINING ONE AMINOSILOXANE GROUP AND TWO PARTICULAR PARA-AMINOBENZALMALONATE GROUPS; COSMETIC COMPOSITIONS CONTAINING SAID DERIVATIVES; USES OF SAID S-TRIAZINE DERIVATIVES L'OREAL (FR) 2009-06-18 WO disclosed
US-4457911-A Dialkyl malonates as organic sunscreen adjuvants VAN DYK & COMPANY INC. (US) 1984-07-03 US disclosed
EP-0100651-A1 Dialkyl malonates as organic suncreen adjuvants VAN DYK & COMPANY, INC. (US) 1984-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100183530-A1 Cosmetic compositions comprising 4-carboxy-2-pyrrolidinone esters and triazine lipophilic UV-screening agents TYR, PAH, C1S MEN1 1842/4885KMT2A 1434/4885ALDH1A1 358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.