SCHEMBL2155010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18023053	0.93	CYP1A2 (0.55)	CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2
	SCHEMBL14475909	0.92	CYP1A2 (0.61)	CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2
	SCHEMBL14474123	0.91	CYP3A4 (0.57)	CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2
	SCHEMBL2154907	0.91	CYP3A4 (0.57)	CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2
	SCHEMBL14727980	0.90	CYP3A4 (0.56)	CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2
	SCHEMBL14475910	0.90	CYP1A2 (0.56)	CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2
	SCHEMBL14474093	0.90	GBA1 (0.58)	CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2
	SCHEMBL14475860	0.89	CYP1A2 (0.55)	CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2
	SCHEMBL14475907	0.87	CYP1A2 (0.53)	CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2
	SCHEMBL14474102	0.87	CYP1A2 (0.60)	CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.