SCHEMBL21550776

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1257320	0.85	HRH3 (0.51)	HRH3NPC1MAPTHSD17B10SMN1; SMN2
	SCHEMBL6555500	0.84	NPC1 (0.47)	HRH3NPC1TSHRCYP2A13HSD17B10
	SCHEMBL21565656	0.82	HRH3 (0.51)	HRH3SLC2A1SMN1; SMN2CXCR4LMNA
	SCHEMBL1256928	0.79	ALDH1A1 (0.60)	HRH3MAPTSMN1; SMN2ALDH1A1LMNA
	SCHEMBL13783890	0.79	HRH3 (0.82)	HRH3NPC1TSHRMAPTUSP2
	SCHEMBL21550787	0.75	HRH3 (0.55)	HRH3NPC1TSHRMAPTUSP2
	SCHEMBL21551028	0.75	NPC1 (0.47)	HRH3NPC1TSHRCYP2A13SLC2A1
	SCHEMBL29725202	0.75	HRH3 (0.55)	HRH3NPC1TSHRMAPTUSP2
	SCHEMBL29725199	0.75	NPC1 (0.47)	HRH3NPC1TSHRCYP2A13SLC2A1
	SCHEMBL19145771	0.74	SMN1; SMN2 (0.47)	HRH3NPC1CYP2A13HSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.