SCHEMBL21551028

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29725199	1.00	NPC1 (0.47)	NPC1SLC16A3KCNH2CXCR4HRH3
	SCHEMBL21565497	0.84	KCNH2 (0.54)	NPC1SLC16A3KCNH2CXCR4HRH3
	SCHEMBL21550787	0.81	HRH3 (0.55)	NPC1HRH3RAB9ALMNAMAPT
	SCHEMBL29725202	0.81	HRH3 (0.55)	NPC1HRH3RAB9ALMNAMAPT
	SCHEMBL110617	0.79	HRH3 (0.53)	NPC1KCNH2CXCR4HRH3SMN1; SMN2
	SCHEMBL21550535	0.79	LMNA (0.50)	NPC1SLC16A3KCNH2CXCR4HRH3
	SCHEMBL31002170	0.77	CXCR4 (0.50)	NPC1CXCR4HRH3RAB9ASMN1; SMN2
	SCHEMBL23601168	0.76	CXCR4 (0.48)	NPC1SLC16A3KCNH2CXCR4HRH3
	SCHEMBL21550776	0.75	HRH3 (0.51)	NPC1CXCR4HRH3LMNAMAPT
	SCHEMBL21550509	0.75	LMNA (0.46)	NPC1SLC16A3KCNH2CXCR4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.