SCHEMBL21551092

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29725192	1.00	TBK1 (0.48)	TBK1STAT3TP53GPR119POLB
	SCHEMBL1433245	0.85	POLB (0.58)	POLBMEN1KMT2AVEGFAEGLN1
	SCHEMBL30042412	0.84	MEN1 (0.49)	TBK1TP53GPR119POLBMEN1
	SCHEMBL2933302	0.84	MEN1 (0.49)	TBK1TP53GPR119POLBMEN1
	SCHEMBL29101948	0.81	POLB (0.53)	POLBMEN1KMT2AVEGFAEGLN1
	SCHEMBL30520640	0.81	MEN1 (0.50)	TBK1TP53GPR119POLBMEN1
	SCHEMBL15100940	0.80	NSD2 (0.47)	TP53MEN1KMT2AATMVEGFA
	SCHEMBL114519	0.80	VEGFA (0.50)	TBK1TP53GPR119MEN1KMT2A
	SCHEMBL12557699	0.80	KMT2A (0.69)	TP53GPR119POLBMEN1KMT2A
	SCHEMBL1997213	0.80	MEN1 (0.49)	TBK1TP53GPR119POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.