Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | VEGFA | P15692 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.46 |
| ▸ | GPR4 | P46093 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14190954 | 0.88 | GPR4 (0.47) | MEN1KMT2AVEGFAEGLN1MAPT | |
| SCHEMBL1997213 | 0.86 | MEN1 (0.49) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL30042412 | 0.86 | MEN1 (0.49) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL114519 | 0.86 | VEGFA (0.50) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL30584532 | 0.86 | MEN1 (0.49) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL2933302 | 0.86 | MEN1 (0.49) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL12557699 | 0.86 | KMT2A (0.69) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL31298334 | 0.85 | MEN1 (0.51) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL209280 | 0.85 | TBK1 (0.55) | MEN1KMT2AATMVEGFAEGLN1 | |
| SCHEMBL28653662 | 0.85 | MEN1 (0.48) | MEN1KMT2AATMVEGFAEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11660303-B2 | 2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ROR1 activity | KANCERA AB (SE) | 2023-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11660303-B2 | 2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ROR1 activity | ROR1, RORB, RORA | MEN1 1781/4885KMT2A 1417/4885ATM 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.