Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924268 | 0.93 | TDP1 (0.52) | CYP3A4TDP1ALDH1A1TP53MAPK1 | |
| SCHEMBL20438389 | 0.88 | SMN1; SMN2 (0.37) | ALDH1A1ALOX15HSD17B10TSHRMAPT | |
| Bicarbonate SCHEMBL6665758 | 0.83 | ALDH1A1 (0.43) | CYP3A4TDP1ALDH1A1TP53MAPK1 | |
| SCHEMBL20438385 | 0.80 | ALDH1A1 (0.39) | CYP3A4TDP1ALDH1A1TP53MAPK1 | |
| SCHEMBL8629718 | 0.79 | TDP1 (0.45) | CYP3A4TDP1ALDH1A1TP53MAPK1 | |
| SCHEMBL7647702 | 0.78 | ALDH1A1 (0.39) | CYP3A4TDP1ALDH1A1TP53MAPK1 | |
| SCHEMBL14016091 | 0.77 | MAPT (0.31) | MAPTSMN1; SMN2 | |
| SCHEMBL29763170 | 0.75 | ALDH1A1 (0.45) | CYP3A4TDP1ALDH1A1TP53MAPK1 | |
| SCHEMBL625329 | 0.74 | ALDH1A1 (0.48) | CYP3A4TDP1ALDH1A1TP53MAPK1 | |
| SCHEMBL21831591 | 0.74 | ALDH1A1 (0.48) | CYP3A4TDP1ALDH1A1TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519532-A1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | Chevron Phillips Chemical Company LP (US) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011082192-A1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-07-07 | — | — | WO | disclosed |