Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21831591 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1CYP3A4MAPK1ALOX15 | |
| Sulfuric Acid SCHEMBL999405 | 0.90 | ALDH1A1 (0.42) | ALDH1A1TDP1CYP3A4MAPK1ALOX15 | |
| SCHEMBL924268 | 0.80 | TDP1 (0.52) | ALDH1A1TDP1CYP3A4MAPK1ALOX15 | |
| SCHEMBL4201252 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TDP1CYP3A4MAPK1ALOX15 | |
| SCHEMBL80210 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRMAPTCYP2C19 | |
| SCHEMBL3675301 | 0.78 | ESR1 (0.44) | ALDH1A1TDP1CYP3A4ALOX15RECQL | |
| SCHEMBL6655727 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TDP1CYP3A4MAPK1ALOX15 | |
| SCHEMBL9690365 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL3137153 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRMAPTCYP2C19 | |
| Bicarbonate SCHEMBL6665758 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TDP1CYP3A4MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3111915-B1 | CATALYSED DYE SYSTEMS | UNIV LEEDS INNOVATIONS LTD (GB) | 2017-10-04 | — | — | EP | claimed |
| EP-3111915-A1 | CATALYSED DYE SYSTEMS | UNIVERSITY OF LEEDS (GB) | 2017-01-04 | — | — | EP | claimed |
| EP-2448545-B1 | CATALYSED DYE SYSTEMS | UNIV LEEDS (GB) | 2016-09-07 | — | — | EP | claimed |
| US-8608810-B2 | Hair colorant compositions comprising 3-amino-2,6-dimethylphenol and 1,4-phenylenediamine-type developers, methods, and kits comprising the compositions | THE PROCTER & GAMBLE COMPANY (US) | 2013-12-17 | — | — | US | claimed |
| US-20130255004-A1 | Hair colorant compositions comprising 3-amino-2,6-dimethylphenol and 1,4-phenylenediamine-type developers, methods, and kits comprising the compositions | THE PROCTER & GAMBLE COMPANY (US) | 2013-10-03 | — | — | US | claimed |
| US-8535391-B2 | Catalysed dye systems | UNIVERSITY OF LEEDS (GB) | 2013-09-17 | — | — | US | claimed |
| US-20120110751-A1 | Catalysed Dye Systems | UNIVERSITY OF LEEDS (GB) | 2012-05-10 | — | — | US | claimed |
| EP-2448545-A2 | CATALYSED DYE SYSTEMS | The University Of Leeds (GB) | 2012-05-09 | — | — | EP | claimed |
| WO-2011000892-A2 | CATALYSED DYE SYSTEMS | UNIVERSITY OF LEEDS (GB) | 2011-01-06 | — | — | WO | claimed |
| US-7066968-B2 | Efficient two-step method of coloring and lightening hair with less damage | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2006-06-27 | — | — | US | claimed |
| US-6579326-B2 | For dyeing hair | L'OREAL S.A. (FR) | 2003-06-17 | — | — | US | claimed |
| US-20030074748-A1 | Method and composition for the gradual permanent coloring of hair | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-04-24 | — | — | US | claimed |
| US-6537328-B1 | Hair dye | L'OREAL S.A. (FR) | 2003-03-25 | — | — | US | claimed |
| US-20030028975-A9 | COMPOSITIONS FOR DYEING KERATIN FIBERS, CONTAINING CATIONIC INDOLIZINE DERIVATIVES, AND DYEING PROCESS | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | claimed |
| US-6379399-B1 | HAIR DYES WITH OXIDATION COLOR DYES WITH 2-AMINO-8-HYDROXY QUINOLINE AND HYDROGEN PEROXIDE, APPLYING, RINSING, SHAMPOO AND DRYING WITH COUPLERS | BRISTOL-MYERS SQUIBB COMPANY | 2002-04-30 | — | — | US | claimed |
| US-20010044974-A1 | Compositions for dyeing keratin fibers, containing cationic indolizine derivatives, and dyeing process | BRETON PHILIPPE (FR) | 2001-11-29 | — | — | US | claimed |
| WO-2001060327-A1 | OXIDATIVE HAIR DYEING SYSTEM AND PROCESS FOR PROVIDING MORE EQUALIZED COLORATION ON NEW AND OLD GROWTH HAIR | CLAIROL INCORPORATED (US) | 2001-08-23 | — | — | WO | claimed |
| US-6093219-A | Composition for the oxidation dyeing of keratin fibers, comprising at least two oxidation bases and an indole coupler, and dyeing process | L'OREAL (FR) | 2000-07-25 | — | — | US | claimed |
| EP-0728463-B1 | Composition for oxidation dyeing of keratinous fibers comprising at least two oxidation bases and an indole coupleur and process for dyeing | OREAL (FR) | 1999-07-21 | — | — | EP | claimed |
| EP-0728463-A1 | Composition for oxidation dyeing of keratinous fibers comprising at least two oxidation bases and an indole coupleur and process for dyeing | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120110751-A1 | Catalysed Dye Systems | FH, TYR, POLR1C | ALDH1A1 292/4885TDP1 1899/4885CYP3A4 174/4885 |
| US-20010044974-A1 | Compositions for dyeing keratin fibers, containing cationic indolizine derivatives, and dyeing process | KRT18, INMT, KMO | ALDH1A1 2691/4885TDP1 2965/4885CYP3A4 1696/4885 |
| US-20130255004-A1 | Hair colorant compositions comprising 3-amino-2,6-dimethylphenol and 1,4-phenylenediamine-type developers, methods, and kits comprising the compositions | DDC, DDT, QDPR | ALDH1A1 301/4885TDP1 944/4885CYP3A4 1442/4885 |
| US-20030028975-A9 | COMPOSITIONS FOR DYEING KERATIN FIBERS, CONTAINING CATIONIC INDOLIZINE DERIVATIVES, AND DYEING PROCESS | KRT18, INMT, KMO | ALDH1A1 2493/4885TDP1 3046/4885CYP3A4 1685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.