⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14072857 | 0.92 | — | — | |
| SCHEMBL8339642 | 0.89 | — | — | |
| SCHEMBL18531894 | 0.84 | — | — | |
| SCHEMBL11929981 | 0.81 | — | — | |
| SCHEMBL14749857 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL14749875 | 0.74 | CXCR4 (0.32) | — | |
| SCHEMBL21533872 | 0.74 | — | — | |
| SCHEMBL17433229 | 0.74 | — | — | |
| SCHEMBL17465655 | 0.72 | — | — | |
| SCHEMBL403605 | 0.69 | OPRM1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226107-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR | HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO., LTD. (CN) | 2024-07-11 | — | — | US | disclosed |
| US-10669239-B2 | Tetrahydronaphthyl urea derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2020-06-02 | — | — | US | disclosed |
| US-20190337897-A1 | NOVEL TETRAHYDRONAPHTHYL UREA DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2019-11-07 | — | — | US | disclosed |