Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 6/20 | 0.39 |
| ▸ | CASP7 | P55210 | 5/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227004 | 1.00 | MCOLN3 (0.42) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL1569029 | 0.87 | CYP2D6 (0.46) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL1569030 | 0.87 | CYP2D6 (0.46) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL9214135 | 0.87 | CYP2D6 (0.46) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL26077272 | 0.86 | MCOLN3 (0.45) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL9686466 | 0.80 | CYP2D6 (0.47) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL4595283 | 0.80 | CYP2D6 (0.47) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL7565543 | 0.76 | ALDH1A1 (0.43) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL7565547 | 0.76 | ALDH1A1 (0.43) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL10845792 | 0.74 | CYP2D6 (0.47) | MCOLN3L3MBTL1POLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790871-B1 | FURIN INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-01-24 | — | — | EP | disclosed |
| EP-3790871-A1 | FURIN INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2021-03-17 | — | — | EP | disclosed |
| WO-2019215341-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-11-14 | — | — | WO | disclosed |