Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15988689 | 0.81 | IDO1 (0.43) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL5868810 | 0.78 | LMNA (0.45) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL506452 | 0.77 | KDM4E (0.41) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL4949422 | 0.74 | LMNA (0.43) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL12622649 | 0.74 | POLB (0.52) | MAPTKDM4EKMT2AMEN1RAB9A | |
| SCHEMBL16919016 | 0.74 | GSK3B (0.41) | GAAMAPTKMT2AMEN1RAB9A | |
| SCHEMBL3056218 | 0.73 | KDM4E (0.42) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL24577695 | 0.70 | LMNA (0.39) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL17257563 | 0.68 | KMT2A (0.38) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL17257561 | 0.68 | KMT2A (0.38) | GAAMAPTKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782565-B1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | BAYER IP GMBH (DE) | 2019-11-06 | — | — | EP | disclosed |