Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24577695 | 0.83 | LMNA (0.39) | LMNANPSR1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL3056218 | 0.82 | KDM4E (0.42) | LMNANPSR1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL506452 | 0.82 | KDM4E (0.41) | LMNANPSR1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5868810 | 0.80 | LMNA (0.45) | LMNANPSR1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL22031739 | 0.79 | GPR35 (0.46) | LMNANPSR1RAB9APTPN2PTPN1 | |
| SCHEMBL12622649 | 0.79 | POLB (0.52) | LMNANPSR1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL4404656 | 0.75 | DHODH (0.43) | LMNANPSR1RAB9APTPN2PTPN1 | |
| SCHEMBL9116385 | 0.75 | LMNA (0.36) | LMNANPSR1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL9116375 | 0.75 | LMNA (0.36) | LMNANPSR1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL21554150 | 0.74 | GAA (0.42) | LMNANPSR1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230309388-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2023-09-28 | — | — | US | disclosed |
| US-9029499-B2 | Semiconducting polymers | UNIVERSITY OF CHICAGO (US) | 2015-05-12 | — | — | US | disclosed |
| US-9029499-B2 | Semiconducting polymers | UNIVERSITY OF CHICAGO (US) | 2015-05-12 | — | — | US | disclosed |
| EP-2307483-B1 | SEMICONDUCTING POLYMERS | UNIV CHICAGO (US) | 2015-04-22 | — | — | EP | disclosed |
| US-20140235817-A1 | SEMICONDUCTING POLYMERS | UNIVERSITY OF CHICAGO (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140235817-A1 | SEMICONDUCTING POLYMERS | UNIVERSITY OF CHICAGO (US) | 2014-08-21 | — | — | US | disclosed |
| US-8653228-B2 | Semiconducting polymers | UNIVERSITY OF CHICAGO (US) | 2014-02-18 | — | — | US | disclosed |
| US-8653228-B2 | Semiconducting polymers | UNIVERSITY OF CHICAGO (US) | 2014-02-18 | — | — | US | disclosed |
| US-8436134-B2 | Semiconducting polymers | UNIVERSITY OF CHICAGO (US) | 2013-05-07 | — | — | US | disclosed |
| US-20110124822-A1 | SEMICONDUCTING POLYMERS | NATIONAL SCIENCE FOUNDATION | 2011-05-26 | — | — | US | disclosed |
| US-7041685-B2 | Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2006-05-09 | — | — | US | disclosed |
| US-20050154012-A1 | Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2005-07-14 | — | — | US | disclosed |
| EP-1406632-A2 | SUBSTITUTED 3-ARYL-5-ARYL- 1,2,4]-OXADIAZOLES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | Cytovia, Inc. (US) | 2004-04-14 | — | — | EP | disclosed |
| US-20030045546-A1 | Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2003-03-06 | — | — | US | disclosed |
| WO-2002100826-A2 | SUBSTITUTED 3-ARYL-5-ARYL-[1,2,4]-OXADIAZOLES AND ANALOGS | CYTOVIA, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |
| US-4025505-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045546-A1 | Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP3, CASP1, API5 | LMNA 1419/4885NPSR1 4000/4885POLB 2836/4885 |
| US-20230309388-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | OCIAD1, OCIAD2, SLCO4C1 | LMNA 2062/4885NPSR1 4548/4885POLB 2113/4885 |
| US-20050154012-A1 | Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP3, CASP1, CASP4 | LMNA 1844/4885NPSR1 4405/4885POLB 3317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.