Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29944352 | 1.00 | FFAR3 (0.41) | — | |
| SCHEMBL128546 | 0.84 | — | — | |
| Lithium SCHEMBL31563576 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL31199141 | 0.81 | — | — | |
| Butyric Acid SCHEMBL2156548 | 0.79 | FFAR3 (0.62) | — | |
| Acetic Acid SCHEMBL10415152 | 0.76 | FFAR3 (0.35) | — | |
| SCHEMBL2341666 | 0.76 | GABRR1 (0.37) | — | |
| Bicarbonate SCHEMBL167201 | 0.74 | FFAR3 (0.44) | — | |
| Bicarbonate SCHEMBL15967910 | 0.74 | FFAR3 (0.44) | — | |
| Acetic Acid SCHEMBL28712076 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805302-B1 | HYDROLYSIS OF ESTER BONDS WITH LIPASE | NOVOZYMES AS (DK) | 2012-08-15 | — | — | EP | disclosed |
| CN-102212509-A | Hydrolysis of ester bonds with lipase | NOVOZYMES AS | 2011-10-12 | — | — | CN | disclosed |
| US-7972831-B2 | Lipases from thermophilic anaerobes | NOVOZYMES A/S (DK) | 2011-07-05 | — | — | US | disclosed |
| US-20090029410-A1 | Lipases from Thermophilic Anaerobes | NOVOZYMES A/S (DK) | 2009-01-29 | — | — | US | disclosed |
| CN-101035894-A | Hydrolysis of ester bonds with lipase | NOVOZYMES AS (DK) | 2007-09-12 | — | — | CN | disclosed |
| EP-1805302-A1 | HYDROLYSIS OF ESTER BONDS WITH LIPASE | Novozymes A/S (DK) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006037334-A1 | HYDROLYSIS OF ESTER BONDS WITH LIPASE | NOVOZYMES A/S (DK) | 2006-04-13 | — | — | WO | disclosed |