Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL2587933 | 0.82 | — | — | |
| Acetic Acid SCHEMBL2155455 | 0.79 | — | — | |
| Butyric Acid SCHEMBL8458708 | 0.79 | FFAR3 (1.00) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL991717 | 0.79 | FFAR3 (1.00) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL5703921 | 0.79 | FFAR3 (1.00) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL4446516 | 0.79 | FFAR3 (1.00) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL1332215 | 0.79 | — | — | |
| Butyric Acid SCHEMBL8457839 | 0.79 | FFAR3 (1.00) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL20678495 | 0.79 | — | — | |
| Butyric Acid SCHEMBL339305 | 0.79 | FFAR3 (1.00) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187737-B2 | Mutants of a pseudomonas glumae butynol esterase | BASF SE (DE) | 2015-11-17 | — | — | US | disclosed |
| EP-1805302-B1 | HYDROLYSIS OF ESTER BONDS WITH LIPASE | NOVOZYMES AS (DK) | 2012-08-15 | — | — | EP | disclosed |
| US-8008051-B2 | Butynol I esterase | BASF AKTIENGESELLSCHAFT (DE) | 2011-08-30 | — | — | US | disclosed |
| US-7972831-B2 | Lipases from thermophilic anaerobes | NOVOZYMES A/S (DK) | 2011-07-05 | — | — | US | disclosed |
| US-20100196970-A1 | Butynol I esterase | HAUER BERNHARD | 2010-08-05 | — | — | US | disclosed |
| US-20100068760-A1 | PROTEINS WITH ESTERASE ACTIVITY | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
| US-7531331-B2 | Butynol I esterase | BASF AKTIENGESELLSCHAFT (DE) | 2009-05-12 | — | — | US | disclosed |
| US-20090029410-A1 | Lipases from Thermophilic Anaerobes | NOVOZYMES A/S (DK) | 2009-01-29 | — | — | US | disclosed |
| EP-1805302-A1 | HYDROLYSIS OF ESTER BONDS WITH LIPASE | Novozymes A/S (DK) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006037334-A1 | HYDROLYSIS OF ESTER BONDS WITH LIPASE | NOVOZYMES A/S (DK) | 2006-04-13 | — | — | WO | disclosed |
| US-20050181472-A1 | Butinol i esterase | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | US | disclosed |