Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1592871 | 0.91 | BACE1 (0.47) | XPO1ALDH1A1L3MBTL1BACE1SLC2A1 | |
| SCHEMBL21556198 | 0.79 | XPO1 (0.44) | XPO1 | |
| SCHEMBL13906932 | 0.78 | SMN1; SMN2 (0.42) | XPO1ALDH1A1L3MBTL1BACE1MAPT | |
| SCHEMBL1592872 | 0.75 | BACE1 (0.46) | XPO1ALDH1A1L3MBTL1BACE1KDM4E | |
| SCHEMBL8138653 | 0.71 | XPO1 (0.61) | XPO1ALDH1A1MAPTPDE10AKDM4E | |
| SCHEMBL1592460 | 0.70 | XPO1 (0.47) | XPO1CDK2 | |
| SCHEMBL21556185 | 0.69 | XPO1 (0.44) | XPO1MAPTSMN1; SMN2HPGD | |
| SCHEMBL1592486 | 0.68 | XPO1 (0.48) | XPO1ALDH1A1L3MBTL1 | |
| SCHEMBL18197816 | 0.68 | XPO1 (0.46) | XPO1 | |
| SCHEMBL1592489 | 0.68 | XPO1 (0.45) | XPO1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567035-A1 | N-SUBSTITUTED 2,5-DIOXO-AZOLINE COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Canbas Co. Ltd. (JP) | 2019-11-13 | — | — | EP | disclosed |