Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 9/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1592460 | 0.91 | XPO1 (0.47) | XPO1 | |
| SCHEMBL1592387 | 0.83 | XPO1 (0.53) | XPO1 | |
| SCHEMBL21556198 | 0.81 | XPO1 (0.44) | XPO1 | |
| SCHEMBL1592462 | 0.76 | XPO1 (0.38) | XPO1 | |
| SCHEMBL23872048 | 0.72 | XPO1 (0.52) | XPO1 | |
| SCHEMBL1592361 | 0.71 | XPO1 (0.67) | XPO1 | |
| SCHEMBL21556239 | 0.68 | XPO1 (0.41) | XPO1 | |
| SCHEMBL1592388 | 0.68 | XPO1 (0.35) | XPO1 | |
| SCHEMBL1592533 | 0.68 | XPO1 (0.59) | XPO1 | |
| SCHEMBL30176857 | 0.67 | RORC (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3088397-A1 | COMPOUNDS THAT ABROGATE THE CELL CYCLE G2 CHECKPOINT FOR USE IN THE TREATMENT OF CANCER | Canbas Co. Ltd. (JP) | 2016-11-02 | — | — | EP | disclosed |