SCHEMBL1592871

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21556239	0.91	XPO1 (0.41)	BACE1XPO1ALDH1A1L3MBTL1MAPT
	SCHEMBL1592872	0.84	BACE1 (0.46)	BACE1XPO1ALDH1A1L3MBTL1ACP1
	SCHEMBL1592460	0.78	XPO1 (0.47)	XPO1
	SCHEMBL20880362	0.75	XPO1 (0.54)	XPO1
	SCHEMBL1592486	0.74	XPO1 (0.48)	XPO1ALDH1A1L3MBTL1
	SCHEMBL8137397	0.73	BACE1 (0.63)	BACE1ALDH1A1L3MBTL1ACP1MCHR1
	SCHEMBL8138653	0.72	XPO1 (0.61)	XPO1ALDH1A1MAPTKMT2ACYP1A2
	SCHEMBL1592489	0.72	XPO1 (0.45)	XPO1MAPT
	SCHEMBL20880320	0.72	XPO1 (0.46)	XPO1ALDH1A1L3MBTL1
	SCHEMBL19117639	0.71	BACE1 (0.64)	BACE1ALDH1A1L3MBTL1ACP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.