SCHEMBL21556868

SCHEMBL21556868

C=CC(=O)OCCc1ccc(OC(=O)/C=C/c2ccc(-c3ccc(OCCCCCCOC(C)(O)C=C)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.43
CA4 P22748 3/20 0.43
CA6 P23280 3/20 0.43
CA5A P35218 3/20 0.43
CA7 P43166 3/20 0.43
CA9 Q16790 3/20 0.43
CA14 Q9ULX7 3/20 0.43
CA5B Q9Y2D0 3/20 0.43
CA1 P00915 2/20 0.43
MET P08581 3/20 0.43
PPARA Q07869 5/20 0.39
PPARG P37231 4/20 0.39
AKR1B10 O60218 2/20 0.39
AKR1B1 P15121 2/20 0.39
MAOB P27338 1/20 0.39
THRB P10828 3/20 0.38
HTR7 P34969 1/20 0.36
APP P05067 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3437306 0.89 CA12 (0.51) CA12CA4CA6CA5ACA7
SCHEMBL3437320 0.88 CA12 (0.52) CA12CA4CA6CA5ACA7
SCHEMBL22219379 0.84 CA12 (0.46) CA12CA4CA6CA5ACA7
SCHEMBL22219380 0.84 CA12 (0.46) CA12CA4CA6CA5ACA7
SCHEMBL3437307 0.83 CA12 (0.46) CA12CA4CA6CA5ACA7
SCHEMBL3437297 0.82 MET (0.58) CA12CA4CA6CA5ACA7
SCHEMBL3437285 0.82 MET (0.58) CA12CA4CA6CA5ACA7
SCHEMBL18926017 0.81 CA12 (0.46) CA12CA4CA6CA5ACA7
SCHEMBL13750820 0.81 THRB (0.51) CA12CA4CA6CA5ACA7
SCHEMBL3437309 0.81 THRB (0.47) PPARAAKR1B10AKR1B1THRBAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3239273-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DAINIPPON INK & CHEMICALS (JP) 2019-11-13 EP disclosed