Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18401371 | 0.81 | ADRB2 (0.42) | ADRB2HIF1ATSHRADRA1ALMNA | |
| SCHEMBL21556959 | 0.80 | BCAT2 (0.42) | ADRB2HIF1ATSHRADRA1ALMNA | |
| SCHEMBL20852551 | 0.79 | BCAT2 (0.42) | HIF1ACYP2C9BLMKDM4ESMN1; SMN2 | |
| SCHEMBL18401331 | 0.78 | ADRB2 (0.42) | ADRB2HIF1ATSHRADRA1ALMNA | |
| SCHEMBL18401387 | 0.78 | ADRB2 (0.42) | ADRB2HIF1ATSHRADRA1ALMNA | |
| SCHEMBL21556957 | 0.78 | ADRB2 (0.42) | ADRB2HIF1ATSHRADRA1ALMNA | |
| SCHEMBL13840700 | 0.78 | ADRB2 (0.46) | ADRB2HIF1ATSHRADRA1ALMNA | |
| SCHEMBL21556942 | 0.78 | ADRB2 (0.42) | ADRB2HIF1ATSHRADRA1ALMNA | |
| SCHEMBL20852549 | 0.73 | HIF1A (0.61) | ADRB2HIF1ATSHRADRA1ALMNA | |
| SCHEMBL14769097 | 0.73 | HIF1A (0.61) | ADRB2HIF1ATSHRADRA1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |