Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | APEX1 | P27695 | 3/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152574 | 0.82 | ADRA2A (0.42) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL1704057 | 0.79 | ADRB2 (0.65) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL14138074 | 0.75 | ADRB2 (0.55) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL1691820 | 0.74 | ADRA2A (1.00) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL13158583 | 0.74 | ADRA2A (1.00) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL21556889 | 0.74 | ADRB2 (0.59) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL15811782 | 0.74 | ADRB2 (0.59) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL7151317 | 0.72 | ADRA2A (0.40) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL7150504 | 0.72 | APEX1 (0.38) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL7147017 | 0.70 | ADRA2A (0.39) | ADRB2ADRA2AADRA2BADRA2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |