Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21556997 | 0.81 | SHBG (0.49) | EPHX2NR1H4HDAC3HDAC8HDAC6 | |
| SCHEMBL11954 | 0.80 | EPHX2 (0.59) | EPHX2NR1H4HDAC3HDAC8HDAC6 | |
| SCHEMBL21556965 | 0.79 | PTPN1 (0.33) | KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL20852573 | 0.78 | NR1H4 (0.38) | EPHX2NR1H4HDAC3MEN1CYP1A2 | |
| SCHEMBL20077884 | 0.77 | EPHX1 (0.47) | EPHX1 | |
| SCHEMBL15125586 | 0.76 | EPHX2 (0.55) | EPHX2NR1H4HDAC3HDAC8HDAC6 | |
| SCHEMBL3672272 | 0.76 | CYP2C9 (0.48) | MEN1CYP2C19KMT2ACA1CA2 | |
| SCHEMBL18232437 | 0.74 | ALDH1A1 (0.42) | MEN1CYP1A2CYP2C19KMT2ACA2 | |
| SCHEMBL8399380 | 0.74 | MEN1 (0.51) | MEN1CYP2C19KMT2ACA1CA2 | |
| SCHEMBL4020664 | 0.74 | IDO1 (0.56) | EPHX2HDAC3HDAC8HDAC6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |