Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 6/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | DRD1 | P21728 | 3/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22826941 | 0.84 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL20852478 | 0.84 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL13840704 | 0.84 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL19361305 | 0.84 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL31392616 | 0.76 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL10445887 | 0.75 | MAPT (0.60) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL7150196 | 0.75 | TAAR1 (0.54) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL31392618 | 0.75 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL20852549 | 0.74 | HIF1A (0.61) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL14769097 | 0.74 | HIF1A (0.61) | ADRA2AADRA2BADRA2CADRA1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |