Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19738690 | 0.83 | HTT (0.49) | SMN1; SMN2NPC1HTTALDH1A1MITF | |
| SCHEMBL1627207 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1HTTALDH1A1MITF | |
| SCHEMBL23188697 | 0.81 | NPC1 (0.36) | SMN1; SMN2NPC1HTTALDH1A1MITF | |
| SCHEMBL9828927 | 0.73 | GAA (0.57) | SMN1; SMN2NPC1HTTALDH1A1MITF | |
| SCHEMBL13620347 | 0.71 | KAT2B (0.36) | SMN1; SMN2NPC1HTTALDH1A1MITF | |
| SCHEMBL19738637 | 0.71 | HTT (0.47) | SMN1; SMN2NPC1HTTALDH1A1MITF | |
| SCHEMBL12160455 | 0.70 | KAT2B (0.56) | ALDH1A1RAB9ANPSR1GAAMAPT | |
| SCHEMBL2323909 | 0.68 | GAA (0.41) | SMN1; SMN2NPC1HTTALDH1A1MITF | |
| SCHEMBL11946605 | 0.66 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1HTTALDH1A1KMT2A | |
| SCHEMBL10366081 | 0.66 | BPTF (0.46) | SMN1; SMN2NPC1HTTALDH1A1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419096-B1 | STABILIZATION OF RADIOPHARMACEUTICAL COMPOSITIONS USING ASCORBIC ACID | LANTHEUS MEDICAL IMAGING INC (US) | 2019-11-13 | — | — | EP | disclosed |