Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 3/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HTT | P42858 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12160455 | 0.81 | KAT2B (0.56) | KAT2BBRD9ALDH1A1MAPTGAA | |
| SCHEMBL14385184 | 0.80 | HTT (0.50) | ALDH1A1HTTSMN1; SMN2NPC1MITF | |
| SCHEMBL13620346 | 0.78 | GRIA1 (0.39) | KAT2BBRD9GABRA1GABRB2ALDH1A1 | |
| SCHEMBL1627207 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1HTTSMN1; SMN2NPC1MITF | |
| SCHEMBL10366081 | 0.76 | BPTF (0.46) | KAT2BBRD9ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9828927 | 0.76 | GAA (0.57) | KAT2BALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL2326495 | 0.72 | HTR2A (0.41) | KAT2BALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL2323909 | 0.71 | GAA (0.41) | ALDH1A1HTTSMN1; SMN2NPC1MITF | |
| SCHEMBL21557032 | 0.71 | SMN1; SMN2 (0.37) | ALDH1A1HTTSMN1; SMN2NPC1MITF | |
| SCHEMBL9664481 | 0.70 | RAB9A (0.54) | ALDH1A1HTTSMN1; SMN2NPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123264-A1 | Heterocyclic derivatives as abnormal cannabidiols agents for lowering intraocular pressure | Allergan, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2007127711-A2 | ABNORMAL CANNABIDIOLS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | ALLERGAN, INC. (US) | 2007-11-08 | — | — | WO | disclosed |