Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MITF | O75030 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372838 | 0.85 | HTT (0.38) | GAAKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL2361037 | 0.83 | HTT (0.54) | GAAKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL9828927 | 0.83 | GAA (0.57) | GAAKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL27692058 | 0.82 | PKM (0.41) | ALDH1A1NPSR1PKMLMNATYR | |
| SCHEMBL10824672 | 0.81 | KMT2A (0.41) | GAAKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL27691970 | 0.75 | HTT (0.42) | GAAKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL2326495 | 0.75 | HTR2A (0.41) | GAAKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL23401337 | 0.74 | POLB (0.44) | KMT2AALDH1A1HTTPOLBPKM | |
| SCHEMBL19809108 | 0.73 | TDP1 (0.39) | ALDH1A1POLBNPSR1LMNATYR | |
| SCHEMBL12160455 | 0.73 | KAT2B (0.56) | GAAALDH1A1RAB9AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210187131-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2021-06-24 | — | — | US | disclosed |
| US-10842892-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | LANTHEUS MEDICAL IMAGING, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190290788-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2019-09-26 | — | — | US | disclosed |
| US-10022462-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-07-17 | — | — | US | disclosed |
| EP-3323810-A2 | AUTOMATED REACTION SYSTEM, CASSETTE AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2018-05-23 | — | — | EP | disclosed |
| US-20170258947-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-09-14 | — | — | US | disclosed |
| EP-2534136-B1 | METHODS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING INC (US) | 2017-09-06 | — | — | EP | disclosed |
| US-9603951-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-03-28 | — | — | US | disclosed |
| CN-102858752-A | Method and apparatus for synthesizing imaging agents and intermediates thereof | LANTHEUS MEDICAL IMAGING INC | 2013-01-02 | — | — | CN | disclosed |
| WO-2011097649-A2 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2011-08-11 | — | — | WO | disclosed |
| EP-1713512-A4 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2009-01-07 | — | — | EP | disclosed |
| EP-1713512-A2 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | Bristol-Myers Squibb Pharma Company (US) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005079391-A2 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290788-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | TNNI3, FABP3, MPI | GAA 846/4885KMT2A 4371/4885ALDH1A1 1208/4885 |
| US-20210187131-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | TNNI3, FABP3, MPI | GAA 846/4885KMT2A 4371/4885ALDH1A1 1208/4885 |
| US-10022462-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | TNNI3, FABP3, MPI | GAA 846/4885KMT2A 4371/4885ALDH1A1 1208/4885 |
| US-10842892-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | TNNI3, FABP3, MPI | GAA 846/4885KMT2A 4371/4885ALDH1A1 1208/4885 |
| US-20170258947-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | TNNI3, FABP3, MPI | GAA 846/4885KMT2A 4371/4885ALDH1A1 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.