SCHEMBL21557034

SCHEMBL21557034

Cc1cccc2c1Oc1c([Si](C)(C)c3ccccc3)cccc1S2(C)I

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988670 0.71 ESR1 (0.46) ESR1ESR2
SCHEMBL20653585 0.71 ESR1 (0.34) ESR1ESR2
SCHEMBL20653582 0.70 ESR1 (0.36) ESR1ESR2
SCHEMBL28240232 0.70 ESR1 (0.42) ESR1ESR2
SCHEMBL12191049 0.67 ESR1 (0.54) ESR1ESR2
SCHEMBL20653685 0.62
SCHEMBL8441760 0.60 ESR1 (0.39) ESR1ESR2
SCHEMBL2453380 0.60 TSHR (0.41) ESR1ESR2
SCHEMBL63526 0.60 ESR1 (0.70) ESR1ESR2
SCHEMBL12124319 0.59 ESR1 (0.42) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428173-B1 DIBENZO[B,E][1,4]OXASILINE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICES INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2019-11-13 EP disclosed