SCHEMBL63526

SCHEMBL63526

C[Si](C)(c1ccccc1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.70
ESR2 Q92731 1/20 0.70
NR1H2 P55055 2/20 0.54
NR1H3 Q13133 2/20 0.54
HPGD P15428 2/20 0.48
TSHR P16473 3/20 0.39
ACHE P22303 2/20 0.39
LMNA P02545 1/20 0.39
ALOX12 P18054 1/20 0.39
MAPT P10636 1/20 0.37
ALDH1A1 P00352 1/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TP53 P04637 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
MAPK1 P28482 1/20 0.33
CA4 P22748 1/20 0.33
BRD4 O60885 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12191039 0.97 ESR1 (0.75) ESR1ESR2NR1H2NR1H3HPGD
SCHEMBL12191040 0.88 ESR1 (0.58) ESR1ESR2NR1H2NR1H3HPGD
SCHEMBL12972969 0.86 ESR1 (0.62) ESR1ESR2NR1H2NR1H3HPGD
SCHEMBL988671 0.86 ESR1 (0.62) ESR1ESR2NR1H2NR1H3HPGD
SCHEMBL12191049 0.84 ESR1 (0.54) ESR1ESR2NR1H2NR1H3HPGD
SCHEMBL2141372 0.84 ESR1 (0.54) ESR1ESR2NR1H2NR1H3HPGD
SCHEMBL15485716 0.84 ESR1 (0.60) ESR1ESR2NR1H2NR1H3HPGD
Diphenylsulfane SCHEMBL29268628 0.84 ESR1 (0.54) ESR1ESR2NR1H2NR1H3HPGD
SCHEMBL17010940 0.82 ESR1 (0.58) ESR1ESR2NR1H2NR1H3HPGD
SCHEMBL22198379 0.82 ESR1 (0.58) ESR1ESR2NR1H2NR1H3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1088 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116854848-B Preparation method of ultra-high molecular weight poly alpha-olefin 金浦新材料股份有限公司 2026-05-19 CN claimed
US-12306373-B2 Low melting point ionic liquids for infra-red liquid lens design CORNING INCORPORATED (US) 2025-05-20 US claimed
CN-118290662-A Photo-thermal dual-curing 3D printing resin composite material and application thereof 西安近代化学研究所 2024-07-05 CN claimed
CN-112624129-B Method for preparing silicon dioxide aerogel material by continuous heating method 上海应用技术大学 2024-06-04 CN claimed
CN-116854848-A Preparation method of ultra-high molecular weight poly alpha-olefin 金浦新材料股份有限公司 2023-10-10 CN claimed
CN-116199831-A High-temperature-resistant and irradiation-resistant sealing rubber and preparation method thereof 扬州大学 2023-06-02 CN claimed
CN-115547540-A Insulating liquid, high-refractive-index liquid lens and application thereof 上海酷聚科技有限公司 2022-12-30 CN claimed
CN-217511816-U Cracker for synthesizing diphenyl dimethyl silicone oil 浙江置正有机硅有限公司 2022-09-30 CN claimed
CN-217313428-U A reation kettle for preparing diphenyl dimethyl silicon oil 浙江置正有机硅有限公司 2022-08-30 CN claimed
CN-113150285-B Preparation method for synthesizing nitrogen heterocyclic ring modified organic silicon resin by utilizing dehydrogenation coupling reaction 哈尔滨工业大学 2022-08-09 CN claimed
EP-1070110-A2 MICROGEL DISPERSION FOR HYDRAULIC APPARATUS AND PROCESSES THE B.F. GOODRICH COMPANY (US) 2001-01-24 EP claimed
WO-2000050478-A1 NOVEL FORMULATIONS OF ALKYLLITHIUMS WITH IMPROVED THERMAL STABILITY, PROCESSES TO PRODUCE THESE FORMULATIONS AND PROCESSES FOR USING THE SAME TO IMPROVE STABILITY OF LIVING POLYMER CHAIN ENDS FMC CORPORATION (US) 2000-08-31 WO claimed
WO-1999051712-A2 MICROGEL DISPERSION FOR HYDRAULIC APPARATUS AND PROCESSES THE B.F. GOODRICH COMPANY (US) 1999-10-14 WO claimed
CN-1215738-A Improved process for preparation of poly(arylcarbonate)s GEN ELECTRIC (US) 1999-05-05 CN claimed
EP-0890596-A1 Process for the preparation of poly (arylcarbonate)s GENERAL ELECTRIC COMPANY (US) 1999-01-13 EP claimed
EP-0614916-B1 Process for producing polyolefin IDEMITSU PETROCHEMICAL CO (JP) 1998-10-07 EP claimed
US-5627255-A ENGINEERING THERMOPLASTICS TO BE USED IN PLACE OF METALS OR GLASS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1997-05-06 US claimed
US-5605990-A USING CATALYST COMPRISING TITANIUM COMPOUND, ALUMINOXANE, AROMATIC RING-CONTAINING COMPOUND IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1997-02-25 US claimed
EP-0372017-B1 EPOXY RESIN COMPOSITIONS FOR SEALING SEMICONDUCTOR DEVICES LUCKY LTD (KR) 1995-10-11 EP claimed
EP-0614916-A1 Process for producing polyolefin IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-09-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12306373-B2 Low melting point ionic liquids for infra-red liquid lens design IK, CRYZ, CRYAA ESR1 2862/4885ESR2 3177/4885NR1H2 3906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.