Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12884531 | 1.00 | CA1 (0.36) | CA1CA2CA7CA14SLC7A5 | |
| SCHEMBL13588555 | 1.00 | CA1 (0.36) | CA1CA2CA7CA14SLC7A5 | |
| SCHEMBL14266212 | 0.88 | LMNA (0.35) | CA1CA2CA7CA14SLC7A5 | |
| SCHEMBL24634162 | 0.83 | CA1 (0.31) | CA1CA2CA7CA14SLC7A5 | |
| SCHEMBL12868864 | 0.78 | SLC7A5 (0.31) | SLC7A5EPHX1 | |
| SCHEMBL12868891 | 0.78 | SLC7A5 (0.31) | SLC7A5EPHX1 | |
| SCHEMBL18826567 | 0.78 | ALDH1A1 (0.37) | SLC7A5 | |
| SCHEMBL12868871 | 0.78 | SLC7A5 (0.31) | SLC7A5EPHX1 | |
| SCHEMBL19103688 | 0.78 | — | — | |
| SCHEMBL22751128 | 0.78 | EPHX1 (0.31) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877173-B1 | CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS | JENRIN DISCOVERY INC (US) | 2019-11-13 | — | — | EP | disclosed |