Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 8/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 2/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10051691 | 0.73 | VNN1 (0.61) | VNN1LMNAAURKA | |
| SCHEMBL21381217 | 0.65 | VNN1 (0.74) | VNN1 | |
| SCHEMBL2715356 | 0.62 | AURKA (0.52) | IGF1RLMNAAURKARPS6KB1AURKB | |
| SCHEMBL20185754 | 0.61 | VNN1 (1.00) | VNN1 | |
| SCHEMBL10051487 | 0.61 | VNN1 (0.47) | VNN1MAPK14APPAURKAPIP4K2A | |
| SCHEMBL6173735 | 0.61 | MAPK14 (0.81) | MAPK13MAPK9MAPK12MAPK11MAPK14 | |
| SCHEMBL6171671 | 0.61 | MAPK14 (0.85) | MAPK13MAPK9MAPK12MAPK11MAPK14 | |
| SCHEMBL4583051 | 0.61 | IDH1 (0.44) | MAPK14IGF1RAPP | |
| SCHEMBL5093362 | 0.60 | VNN1 (0.55) | VNN1AURKARPS6KB1AURKBPIK3CG | |
| SCHEMBL7418491 | 0.60 | HSD11B1 (0.56) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081568-B1 | COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE | EIP PHARMA LLC (US) | 2019-11-13 | — | — | EP | disclosed |