Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30016781 | 1.00 | FFAR1 (0.39) | FFAR1PPARGPPARDSLC6A4SLC6A3 | |
| SCHEMBL15271104 | 0.88 | HCRTR2 (0.44) | FFAR1PPARGPPARDSLC6A4SLC6A3 | |
| SCHEMBL30041950 | 0.88 | HCRTR2 (0.44) | FFAR1PPARGPPARDSLC6A4SLC6A3 | |
| SCHEMBL15897694 | 0.86 | KDM4C (0.43) | SLC6A4SLC6A3KDM4CMAPTALDH1A1 | |
| SCHEMBL15211430 | 0.84 | ESR1 (0.42) | CA2MAPTALDH1A1 | |
| SCHEMBL31432485 | 0.82 | MTNR1A (0.47) | ACHEMAPTALDH1A1TP53 | |
| SCHEMBL2729054 | 0.82 | GAA (0.36) | FFAR1PPARGPPARDACHEALDH1A1 | |
| SCHEMBL1679129 | 0.82 | MAP3K14 (0.44) | FFAR1PPARGPPARDHCRTR2ALDH1A1 | |
| SCHEMBL31704184 | 0.81 | FFAR1 (0.41) | FFAR1PPARGPPARDHCRTR2CA2 | |
| SCHEMBL13576751 | 0.78 | GLS (0.46) | HCRTR2MAPTALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3566749-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS THEREOF | Medshine Discovery Inc. (CN) | 2019-11-13 | — | — | EP | disclosed |