Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14960673 | 0.84 | SLC6A3 (0.40) | SLC6A3ALDH1A1L3MBTL1 | |
| SCHEMBL29992158 | 0.78 | SLC6A3 (0.41) | SLC6A3MAPTALDH1A1GFERL3MBTL1 | |
| SCHEMBL12401719 | 0.78 | KDM4E (0.47) | SLC6A3MAPTALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL25556641 | 0.75 | CMA1 (0.46) | NR4A2MAPTALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL14059228 | 0.72 | SLC6A3 (0.40) | SLC6A3HSD17B3L3MBTL1 | |
| SCHEMBL6648373 | 0.72 | L3MBTL1 (0.42) | NR4A2SLC6A3HSD17B3MAPTALDH1A1 | |
| SCHEMBL12389716 | 0.70 | CA12 (0.47) | MAPTALDH1A1SMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL21474580 | 0.69 | SLC6A3 (0.44) | SLC6A3HSD17B3MAPTALDH1A1L3MBTL1 | |
| SCHEMBL19202553 | 0.69 | L3MBTL1 (0.39) | NR4A2SLC6A3HSD17B3MAPTALDH1A1 | |
| SCHEMBL7888159 | 0.68 | HSD17B3 (0.34) | NR4A2SLC6A3HSD17B3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3566749-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS THEREOF | Medshine Discovery Inc. (CN) | 2019-11-13 | — | — | EP | disclosed |