SCHEMBL29635323

SCHEMBL29635323

C[C@@H](C(=O)O)N(C)C(=O)CCC(C)(C)SSCCCC(=O)NCCN1C(=O)C=CC1=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ AKT1 P31749 1/20 0.33
▸ OPRM1 P35372 2/20 0.32
▸ OPRD1 P41143 2/20 0.32
▸ OPRK1 P41145 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28888674 0.91 MGLL (0.32) —
SCHEMBL28888675 0.91 MGLL (0.32) —
SCHEMBL29628115 0.91 — —
SCHEMBL29825364 0.84 AKT1 (0.35) AKT1OPRM1OPRD1OPRK1
SCHEMBL17345169 0.82 AKT1 (0.33) AKT1OPRM1OPRD1OPRK1
SCHEMBL22455884 0.81 AKT1 (0.33) AKT1OPRM1OPRD1OPRK1
SCHEMBL30199847 0.80 AKT1 (0.33) AKT1
SCHEMBL21557778 0.79 AKT1 (0.32) AKT1OPRM1OPRD1OPRK1
SCHEMBL19733469 0.78 TLR2 (0.33) —
SCHEMBL29635326 0.78 HSD17B10 (0.34) OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12234212-B2 Peptide conjugates of microtubule-targeting agents as therapeutics Cybrexa 3, Inc. (US) 2025-02-25 — — US disclosed
US-20240067616-A1 PEPTIDE CONJUGATES OF MICROTUBULE-TARGETING AGENTS AS THERAPEUTICS Cybrexa 3, Inc. 2024-02-29 — — US disclosed
US-11555019-B2 Peptide conjugates of microtubule-targeting agents as therapeutics Cybrexa 3, Inc. (US) 2023-01-17 — — US disclosed
EP-3996749-A1 PEPTIDE CONJUGATES OF MICROTUBULE-TARGETING AGENTS AS THERAPEUTICS Cybrexa 3, Inc. (US) 2022-05-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067616-A1 PEPTIDE CONJUGATES OF MICROTUBULE-TARGETING AGENTS AS THERAPEUTICS MAP4, MAP2, TUBB3 AKT1 1982/4885OPRM1 4138/4885OPRD1 4364/4885
US-12234212-B2 Peptide conjugates of microtubule-targeting agents as therapeutics MAP4, MAP2, TUBB3 AKT1 1982/4885OPRM1 4138/4885OPRD1 4364/4885
US-11555019-B2 Peptide conjugates of microtubule-targeting agents as therapeutics MAP4, MAP2, TUBB3 AKT1 1982/4885OPRM1 4138/4885OPRD1 4364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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