SCHEMBL21558067

SCHEMBL21558067

COCCOCC1(C#N)CCCC1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.34
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31629694 0.84
SCHEMBL23086688 0.81 DPP4 (0.36) DPP4
SCHEMBL6201919 0.79 ALDH1A1 (0.36) DPP4
SCHEMBL23086702 0.79 DPP4 (0.46) DPP4
SCHEMBL21558089 0.78 DPP4 (0.40) DPP4
SCHEMBL19601432 0.77
SCHEMBL15960829 0.74 DPP4 (0.35) DPP4CA2
SCHEMBL15354776 0.72
SCHEMBL22262515 0.72 DPP4 (0.33) DPP4
SCHEMBL27281911 0.69 DPP4 (0.41) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12319683-B2 Azabenzimidazole compounds and pharmaceutical NIPPON SHINYAKU CO., LTD. (JP) 2025-06-03 US disclosed
EP-3792260-B1 AZABENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL NIPPON SHINYAKU CO LTD (JP) 2024-09-11 EP disclosed
CN-112368282-B Azabenzimidazole compounds and medicaments 日本新药株式会社 2023-10-13 CN disclosed
US-20210371412-A1 AZABENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL NIPPON SHINYAKU CO., LTD. (JP) 2021-12-02 US disclosed
EP-3792260-A1 AZABENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL Nippon Shinyaku Co., Ltd. (JP) 2021-03-17 EP disclosed
CN-112368282-A Azabenzimidazole compounds and pharmaceuticals 日本新药株式会社 2021-02-12 CN disclosed
WO-2019216294-A1 AZABENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL 日本新薬株式会社 (JP) 2019-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210371412-A1 AZABENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL PAM, CHRM3, AZI2 DPP4 419/4885CA2 91/4885
US-12319683-B2 Azabenzimidazole compounds and pharmaceutical PAM, CHRM3, AZI2 DPP4 419/4885CA2 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.