Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDRD2HTR1BHTR1DHTR1F
The experimentally established mechanism targets of Malic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.94 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | TET2 | Q6N021 | 6/20 | 0.52 |
| ▸ | TET3 | O43151 | 2/20 | 0.52 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.52 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malic Acid SCHEMBL30036315 | 0.97 | — | — | |
| Malic Acid SCHEMBL30036864 | 0.97 | — | — | |
| Malic Acid SCHEMBL31673489 | 0.97 | — | — | |
| Malic Acid SCHEMBL98496 | 0.97 | — | — | |
| Malic Acid SCHEMBL856 | 0.97 | — | — | |
| Malic Acid SCHEMBL28355917 | 0.97 | SMN1; SMN2 (1.00) | SMN1; SMN2SLC22A6TET2TET3TET1 | |
| Malic Acid SCHEMBL31673494 | 0.97 | — | — | |
| Malic Acid SCHEMBL256122 | 0.97 | — | — | |
| Malic Acid SCHEMBL89131 | 0.97 | SMN1; SMN2 (1.00) | SMN1; SMN2SLC22A6TET2TET3TET1 | |
| Malic Acid SCHEMBL14125844 | 0.97 | SMN1; SMN2 (1.00) | SMN1; SMN2SLC22A6TET2TET3TET1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 978 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079104-A | High-purity homogeneous phase titanium-doped ferric phosphate and low-cost preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-20240228813-A9 | Biodegradable Shading Paint | LUMIFORTE HOLDING B.V. (NL) | 2024-07-11 | — | — | US | claimed |
| US-20240132741-A1 | Biodegradable Shading Paint | LUMIFORTE HOLDING B V (NL) | 2024-04-25 | — | — | US | claimed |
| EP-4294884-A1 | BIODEGRADABLE SHADING PAINT | Lumiforte Holding B.V. (NL) | 2023-12-27 | — | — | EP | claimed |
| CN-116997617-A | Biodegradable light-shielding coating | 卢米福特控股有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-114031978-B | Particle-free conductive ink and preparation method and application thereof | 常州时创能源股份有限公司 | 2023-05-26 | — | — | CN | claimed |
| US-11459885-B2 | Workflow for predictive model to select formation damage treatment | HALLIBURTON ENERGY SERVICES, INC. (US) | 2022-10-04 | — | — | US | claimed |
| WO-2022177432-A1 | BIODEGRADABLE SHADING PAINT | LUMIFORTE HOLDING B.V. (NL) | 2022-08-25 | — | — | WO | claimed |
| CN-114057579-A | Method for preparing asymmetric carbonate by rectifying catalytic reaction of symmetric carbonate | 河北工业大学 | 2022-02-18 | — | — | CN | claimed |
| CN-108976126-B | Method for preparing methyl ethyl carbonate through ester exchange reaction | 中国科学院大连化学物理研究所 | 2021-02-02 | — | — | CN | claimed |
| US-7151076-B2 | Low residue well treatment fluids and methods of use | BJ SERVICES COMPANY (US) | 2006-12-19 | — | — | US | claimed |
| EP-1720408-A1 | MIXTURES AND METHODS FOR THE INDUCTION OF RESISTANCE IN PLANTS | ISAGRO S.p.A. (IT) | 2006-11-15 | — | — | EP | claimed |
| WO-2006117517-A2 | ACIDIC TREATMENT FLUIDS COMPRISING SCLEROGLUCAN AND/OR DIUTAN AND ASSOCIATED METHODS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2006-11-09 | — | — | WO | claimed |
| US-20060247135-A1 | Acidic treatment fluids comprising scleroglucan and/or diutan and associated methods | HALLIBURTON ENERGY SERVICES, INC. | 2006-11-02 | — | — | US | claimed |
| WO-2005094580-A1 | MIXTURES AND METHODS FOR THE INDUCTION OF RESISTANCE IN PLANTS | ISAGRO S.P.A. (IT) | 2005-10-13 | — | — | WO | claimed |
| US-20050077044-A1 | Low residue well treatment fluids and methods of use | BJ SERVICES COMPANY (US) | 2005-04-14 | — | — | US | claimed |
| US-6810959-B1 | MODIFIED POLYSACCHARIDES THAT HAVE HYDROPHILIC (E.G., CATIONIC, ANIONIC, NONIONIC OR AMPHOTERIC) GROUPS, SUCH AS POLYMERIC QUATERNARY AMMONIUM SALT OF HYDROXYETHYL CELLULOSE REACTED WITH A TRIMETHYL AMMONIUM SUBSTITUTED EPOXIDE | BJ SERVICES COMPANY, U.S.A. | 2004-11-02 | — | — | US | claimed |
| US-20040152602-A1 | Crosslinking delaying agents for acid fluids | BAKER HUGHES HOLDINGS LLC | 2004-08-05 | — | — | US | claimed |
| US-6310008-B1 | Cross-linked well treating fluids | HALLIBURTON ENERGY SERVICES, INC. | 2001-10-30 | — | — | US | claimed |
| EP-1092835-A1 | Cross-linked aqueous well treating fluids | Halliburton Energy Services, Inc. (US) | 2001-04-18 | — | — | EP | claimed |