SCHEMBL2156190

SCHEMBL2156190

Cc1cn(CCc2nc(N)nc(N)n2)c(C)n1

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
CASP1 P29466 1/20 0.41
HRH4 Q9H3N8 1/20 0.33
RPS6KB1 P23443 1/20 0.31
GSK3B P49841 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2157582 0.82 TSHR (0.51) TSHRCASP1HRH4SMN1; SMN2
SCHEMBL28729581 0.79 TSHR (0.48) TSHRCASP1HRH4SMN1; SMN2
SCHEMBL12958450 0.76 TSHR (0.46) TSHRCASP1HRH4
SCHEMBL15867747 0.75 TSHR (0.44) TSHRCASP1HRH4
SCHEMBL1695647 0.75 TSHR (1.00) TSHRCASP1
SCHEMBL584717 0.74 ALDH1A1 (0.33) TSHRHRH4RPS6KB1GSK3B
SCHEMBL4338963 0.71 GRM5 (0.37) TSHRRPS6KB1GSK3BSMN1; SMN2
SCHEMBL2157361 0.71 TSHR (0.50) TSHRCASP1HRH4
SCHEMBL3877612 0.71 CYP1A2 (0.40) TSHRRPS6KB1GSK3B
Iodide SCHEMBL669031 0.70 GRM5 (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1111972-B1 Flexible printed substrate SONY CHEM & INF DEVICE CORP (JP) 2007-05-23 EP claimed
US-7098267-B2 Polyamic acid varnish composition and a flexible printed board SONY CHEMICALS CORP. (JP) 2006-08-29 US claimed
CN-1213117-C Polyamide acid varnish compsns. and flexible printing base plate SONY CHEMICALS CO LTD (JP) 2005-08-03 CN claimed
US-20050027099-A1 Polyamic acid varnish composition and a flexible printed board SONY CHEMICALS CORP (JP) 2005-02-03 US claimed
US-6805967-B2 Polyamic acid varnish composition and a flexible printed board SONY CHEMICALS CORP. (JP) 2004-10-19 US claimed
EP-1108762-B1 Polyamic acid varnish composition and a flexible printed board SONY CHEMICALS CORP (JP) 2004-09-15 EP claimed
EP-1014765-B1 Flexible printed board, polyamic acid and polyamic acid varnish containing same SONY CHEMICALS CORP (JP) 2003-03-12 EP claimed
US-6395399-B2 METALLIC FOIL, E.G. COPPER, HAVING A POLYIMIDE LAYER PRODUCED BY FORMING A FILM OF A POLYAMIC ACID VARNISH FOLLOWED BY IMIDATING AND HAVING A SPECIFIC EXPANSION COEFFICIENT AND SOFTENING POINT; PRINTED CIRCUITS; NONCURLING SONY CHEMICALS CORP. (JP) 2002-05-28 US claimed
US-20010005730-A1 Polyamic acid varnish composition and a flexible printed board SONY CHEMICALS CORP. 2001-06-28 US claimed
EP-1111972-A2 Flexible printed substrate Sony Chemicals Corporation (JP) 2001-06-27 EP claimed
US-20010004496-A1 Flexible printed substrate SONY CHEMICALS CORP. 2001-06-21 US claimed
EP-1108762-A2 Polyamic acid varnish composition and a flexible printed board Sony Chemicals Corporation (JP) 2001-06-20 EP claimed
EP-1014765-A2 Flexible printed board, polyamic acid and polyamic acid varnish containing same Sony Chemicals Corporation (JP) 2000-06-28 EP claimed
US-4501689-A CONTAINING PYRIDINE OR IMIDAZOLE MODIFIED 5-TRIAZINE TAMURA KAKEN CO., LTD. (JP) 1985-02-26 US claimed
US-8986833-B2 Enamel varnish composition for enamel wire and enamel wire using same LS CABLE LTD. (KR) 2015-03-24 US disclosed
EP-1355518-B1 FLEXIBLE PRINTED WIRING BOARD SONY CHEM & INF DEVICE CORP (JP) 2013-09-25 EP disclosed
US-7972693-B2 Enamel varnish composition for enamel wire and enamel wire using the same LS CABLE LTD. (KR) 2011-07-05 US disclosed
EP-1108762-A2 Polyamic acid varnish composition and a flexible printed board Sony Chemicals Corporation (JP) 2001-06-20 EP disclosed
EP-1014765-A2 Flexible printed board, polyamic acid and polyamic acid varnish containing same Sony Chemicals Corporation (JP) 2000-06-28 EP disclosed
US-4501689-A CONTAINING PYRIDINE OR IMIDAZOLE MODIFIED 5-TRIAZINE TAMURA KAKEN CO., LTD. (JP) 1985-02-26 US disclosed