SCHEMBL21563385

SCHEMBL21563385

C=C1C(=O)OC2C1CCC1(C)CCCC(C)C21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UBE2D3 P61077 2/20 0.49
PKM P14618 5/20 0.43
NLRP3 Q96P20 3/20 0.41
CYP3A4 P08684 4/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
STAT3 P40763 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 4/20 0.40
LMNA P02545 3/20 0.40
TP53 P04637 3/20 0.40
NFKB1 P19838 2/20 0.40
CYP1A2 P05177 2/20 0.40
STAT6 P42226 2/20 0.40
MAPT P10636 2/20 0.40
PTGS2 P35354 2/20 0.40
CASP1 P29466 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14614878 0.80 UBE2D3 (0.48) UBE2D3PKMNLRP3CYP3A4CYP2D6
SCHEMBL17301653 0.75 CYP3A4 (0.52) UBE2D3PKMNLRP3CYP3A4CYP2D6
SCHEMBL15941718 0.75 CYP3A4 (0.52) UBE2D3PKMNLRP3CYP3A4CYP2D6
SCHEMBL31005096 0.71 ICAM1 (0.58) CYP3A4TDP1ALDH1A1CYP1A2MEN1
SCHEMBL31005095 0.71 ICAM1 (0.58) CYP3A4TDP1ALDH1A1CYP1A2MEN1
SCHEMBL18334098 0.70 PKM (0.51) UBE2D3PKMNLRP3CYP3A4CYP2D6
SCHEMBL21527011 0.70 PKM (0.48) UBE2D3PKMNLRP3CYP3A4CYP2D6
SCHEMBL30834932 0.69 UBE2D3 (0.41) UBE2D3PKMNLRP3CYP3A4CYP2D6
SCHEMBL17147754 0.69 PKM (0.55) UBE2D3PKMNLRP3CYP3A4CYP2D6
SCHEMBL17147746 0.69 PKM (0.55) UBE2D3PKMNLRP3CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224882-A1 LIGHT SOURCE SEOUL VIOSYS CO LTD (KR) 2024-07-11 US disclosed
US-20240224882-A1 LIGHT SOURCE SEOUL VIOSYS CO LTD (KR) 2024-07-11 US disclosed
US-11778953-B2 Light source for plant cultivation SEOUL VIOSYS CO., LTD. (KR) 2023-10-10 US disclosed
US-11778953-B2 Light source for plant cultivation SEOUL VIOSYS CO., LTD. (KR) 2023-10-10 US disclosed
US-20220192103-A1 LIGHT SOURCE FOR PLANT CULTIVATION SEOUL VIOSYS CO., LTD. (KR) 2022-06-23 US disclosed
US-20210332062-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2021-10-28 US disclosed
EP-3841869-A1 LIGHT SOURCE FOR PLANT CULTIVATION Seoul Viosys Co., Ltd. (KR) 2021-06-30 EP disclosed
US-11021488-B2 Hetero-substituted cyclic lactone analogues and uses thereof BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2021-06-01 US disclosed
US-20200060099-A1 LIGHT SOURCE FOR PLANT CULTIVATION SEOUL VIOSYS CO., LTD. (KR) 2020-02-27 US disclosed
US-20190345167-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2019-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345167-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF MCL1, BCL9L, DLD UBE2D3 2461/4885PKM 4063/4885NLRP3 4339/4885
US-11021488-B2 Hetero-substituted cyclic lactone analogues and uses thereof MCL1, BCL9L, DLD UBE2D3 2461/4885PKM 4063/4885NLRP3 4339/4885
US-20210332062-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF MCL1, BCL9L, DLD UBE2D3 2461/4885PKM 4063/4885NLRP3 4339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.