Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156927 | 0.89 | ELANE (0.44) | HTR2CP2RX7 | |
| SCHEMBL4387114 | 0.85 | PRMT5 (0.42) | ALDH1A1PRMT5WDR77HSP90AA1KMT2A | |
| SCHEMBL26782491 | 0.80 | ELANE (0.42) | HTR2CP2RX7 | |
| SCHEMBL2156734 | 0.78 | HTR2C (0.51) | HTR2CALDH1A1L3MBTL1KMT2A | |
| SCHEMBL8749775 | 0.78 | HTR2C (0.51) | HTR2CALDH1A1L3MBTL1KMT2A | |
| SCHEMBL1568877 | 0.76 | HTR2C (0.49) | HTR2CALDH1A1L3MBTL1KMT2A | |
| SCHEMBL1568880 | 0.76 | HTR2C (0.49) | HTR2CALDH1A1L3MBTL1KMT2A | |
| SCHEMBL1568398 | 0.75 | HTR2C (0.48) | HTR2CALDH1A1KMT2A | |
| SCHEMBL1568401 | 0.75 | HTR2C (0.48) | HTR2CALDH1A1KMT2A | |
| SCHEMBL7406225 | 0.74 | HTT (0.47) | HTR2CALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973026-B2 | Thienopyrroles as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-07-05 | — | — | US | disclosed |