Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385959 | 0.87 | STAT3 (0.39) | ALDH1A1KMT2APOLBMMP2 | |
| SCHEMBL8577320 | 0.87 | STAT3 (0.39) | ALDH1A1KMT2APOLBMMP2 | |
| SCHEMBL8577324 | 0.87 | STAT3 (0.39) | ALDH1A1KMT2APOLBMMP2 | |
| SCHEMBL2156340 | 0.85 | TDP1 (0.41) | PRMT5WDR77ALDH1A1HSP90AA1KMT2A | |
| SCHEMBL6539545 | 0.83 | CACNA1G (0.43) | ALDH1A1KDM4EKMT2AMMP2 | |
| SCHEMBL6539531 | 0.83 | CACNA1G (0.43) | ALDH1A1KDM4EKMT2AMMP2 | |
| SCHEMBL7364192 | 0.77 | HIF1A (0.42) | KMT2APOLBMMP2 | |
| SCHEMBL2954985 | 0.77 | PRMT5 (0.42) | PRMT5WDR77ALDH1A1HSP90AA1KDM4E | |
| SCHEMBL8580183 | 0.76 | CA2 (0.32) | — | |
| SCHEMBL25320445 | 0.76 | PSMD10 (0.37) | ALDH1A1KMT2APOLBMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105227-A1 | Thienopyrroles As Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-04-23 | — | — | US | disclosed |
| EP-1881989-A1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006119975-A1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105227-A1 | Thienopyrroles As Antiviral Agents | ZC3HAV1, HAVCR2, ZC3HAV1L | PRMT5 3734/4885WDR77 2162/4885ALDH1A1 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.