SCHEMBL21563497

SCHEMBL21563497

Fc1c(F)c(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)c2nsnc2c1Br

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HDAC4 P56524 1/20 0.34
GRIA1 P42261 1/20 0.32
CACNG8 Q8WXS5 1/20 0.32
CACNG2 Q9Y698 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21563623 0.81 KDM4E (0.37) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL21563496 0.78 KDM4E (0.35) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL21202669 0.76 KDM4E (0.42) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL26367633 0.76 KDM4E (0.42) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL13382358 0.74 L3MBTL1 (0.57) KDM4EATML3MBTL1HDAC4GRIA1
SCHEMBL17125597 0.74 L3MBTL1 (0.48) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL31256583 0.74 L3MBTL1 (0.48) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL24416516 0.74 KDM4E (0.32) KDM4EL3MBTL1
SCHEMBL13382384 0.73 L3MBTL1 (0.55) KDM4EATML3MBTL1HDAC4GRIA1
SCHEMBL21563480 0.73 KDM4E (0.41) KDM4EATML3MBTL1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019216573-A1 NITROGEN-CONTAINING CYCLIC COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME 주식회사 엘지화학 (KR) 2019-11-14 WO disclosed